The Maternal, Infant, and Early Childhood Home Visiting (MIECHV) Program supports voluntary, evidence-based home visiting services for at-risk pregnant women and parents with young children up to kindergarten entry. At the federal level, MIECHV has engaged in a strategic approach, the MIECHV Learning Agenda, to develop a portfolio of evidence about the implementation and impacts of MIECHV in multiple settings and contexts. The agenda includes a variety of activities, including performance measurement, continuous quality improvement (CQI), systematic reviews, descriptive research, and implementation and impact evaluation. States and territories receiving funding from MIECHV are encouraged to conduct rigorous state-led evaluations. State-led evaluations address questions of interest to the state and provide new insights on the scale-up and implementation of home visiting programs. MIECHV encourages state awardees to develop their own learning agendas to ensure that they use the best available evidence to improve performance.